Mental StressAs if slowing the aging process and avoiding body-deteriorating habits weren’t enough motivation to stay away from AGEs, more and more scientists are finding a connection between these harmful metabolic byproducts and serious mental illnesses.

The presence of AGEs is often indicative of oxidative stress, which is thought to be a contributing factor in the development of diseases including schizophrenia, ADHD, Parkinson’s, Asperger’s, Alzheimer’s, autism and even cancer. In fact, AGEs are believed to speed up oxidative cell damage, thus accelerating the aging process and increasing the chance of disease development.

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raw meatFor decades, scientists have warned about the dangerous carcinogens associated with grilled foods, but a new study revealed another reason to be wary of overcooking.

The study, completed by the Icahn School of Medicine at Mount Sinai Hospital, showed that a diet high in glycotoxins called advanced glycation end-products (AGEs) – found in high-concentration in well-done meat – is a risk factor in developing age-related dementia.

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Uribarri 2Mount Sinai Medical Center physician Dr. Jaime Uribarri, a member of the AGE Foundation’s advisory board, was cited in a recent article about a study published in the Journal of Alzheimer’s Disease.

The article is titled, “New study postulates the role of dietary advanced glycation end products in the risk of Alzheimer’s disease.” The study in question provides evidence that cooking foods at high temperatures increases the risk of Alzheimer’s disease, thanks to advanced glycation end-products (AGEs).

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GirlChoppingTomatoIf you want to improve your health and appearance, various media sources have some advice for you: lower your advanced glycation end-product (AGE) levels.

More and more AGE-related articles have been popping up online in all regions of the world and on websites covering all sorts of topics. The following are some notable recent mentions of AGEs in the media.

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stack of toastAGE-related articles have been popping up in the media in countries all over the world lately, and now Malaysia can be added to that list.

The Star Online recently featured an article about advanced glycation end-products titled “Beware the Maillard baddies,” which was written by Chris Chan.

The Star is Malaysia’s second-largest English newspaper and has a daily circulation of nearly 300,000. Meanwhile, its website – The Star Online – is among the most popular news sites in the country.

The “Maillard baddies” the article referred to are foods that are products of the Maillard reaction. This reaction takes place when food is fried, grilled, baked or toasted, producing a darkening effect. Examples of this are when bread is baked or toasted, or meat is charred on a grill.

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shutterstock_159823835A recent PRWeb article highlighted research on the effects that dietary AGEs have on the brain and other facets of one’s health. The article, titled Avoiding Harmful Byproducts of Heat-Processed Foods Protects Against Risk of Alzheimer’s Disease and Diabetes,” stated:

“Advanced glycation endproducts, or AGEs, are compounds commonly found in the so-called ‘Western diet,’ and previously have been linked to increased body weight, diabetes, and possibly Alzheimer’s disease. Now, researchers at the Icahn School of Medicine at Mount Sinai have shown that AGEs also cause brain changes similar to Alzheimer’s disease and pre-diabetes.”

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World Alzheimer’s Awareness Month is dedicated to helping people learn more about Alzheimer’s and its effects. As people become more educated about Alzheimer’s disease and its symptoms, many people wonder how to tell the difference between symptoms of early stages of Alzheimer’s and memory loss associated with the normal aging process.

Forgetting an appointment or wandering around a parking lot looking for your car doesn’t necessarily mean you’re developing Alzheimer’s. Here are a few common scenarios and how to tell the difference:

Normal age-related changes

  • Forgetting to pay a bill by the due date
  • Needing help programming a TV or microwave
  • Forgetting this day it is but remembering it later
  • Not remembering a person’s name
  • Forgetting where you parked your car
  • Forgetting details of an experience
  • Misplacing things, then retracing steps to find the

Symptoms of Alzheimer’s 

  • Inability to budget or manage money
  • Not being able to complete basic tasks around the house
  • Losing track of the month or season
  • Not recognizing a family member or close friend
  • Forgetting how to drive a car
  • Forgetting entire experiences
  • Misplacing things and not being able to retrace steps

If you notice these signs in yourself or a loved one, it’s important to see a doctor as soon as possible. Early detection can help you get the maximum benefit from available treatments.


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Copyright 2012 AGE Foundation.