LINK: The Aging Effects of Sugar

As the world becomes more aware of Advanced Glycation End-products (AGEs), more and more articles will start popping up on health sites and blogs about the alarming effects of excess AGEs. Such is the case in this article from Tammy’s Health Articles.


In this treatment, author Ananda Mahoney, a skin care expert, explains the relationship between sugar, glycation, AGEs, and premature aging. Here’s an excerpt:

The process by which sugar ages the skin is called glycation and occurs when excess sugar in our blood stream randomly reacts with proteins (such as collagen) and DNA. The end result of sugar molecules inappropriately binding to protein molecules or DNA is the creation of AGEs or advanced glycation end products. AGEs in the body lead to cross-linking, which occurs when chemical bridges are formed between proteins, creating a harder, less elastic structure or material. This has implications for internal structures such as the arteries, gut lining and brain, significantly contributing to issues such as atherosclerosis, age-related memory loss, cataracts and diabetic complications. However, it can also cause the structural protein of our skin (the collagen fibres) to lose strength and flexibility leading to less skin elasticity and more lines and sagging.

The production of AGEs is directly proportional to the level of circulating glucose in your blood stream i.e. the higher your blood sugar the greater the rate of glycation and cross-linking.

For the complete article, click here.

Ananda is exactly right. Excess sugar leads to the formation of AGEs, and AGEs have been shown to amplify the aging process.

We at the AGE Foundation love finding articles like this. We are seeing that the study of AGEs, along with its practical applications, is finding its way to the mainstream. The general public is now discovering what scholars and researchers have known for years: Excess AGEs can lead to premature aging, organ failure, cell irregularity and even death.


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Copyright 2012 AGE Foundation.