A recent PRWeb article highlighted research on the effects that dietary AGEs have on the brain and other facets of one’s health. The article, titled “Avoiding Harmful Byproducts of Heat-Processed Foods Protects Against Risk of Alzheimer’s Disease and Diabetes,” stated:
“Advanced glycation endproducts, or AGEs, are compounds commonly found in the so-called ‘Western diet,’ and previously have been linked to increased body weight, diabetes, and possibly Alzheimer’s disease. Now, researchers at the Icahn School of Medicine at Mount Sinai have shown that AGEs also cause brain changes similar to Alzheimer’s disease and pre-diabetes.”
The article noted that AGEs are naturally occurring at low levels in the body, but are found in high levels mostly in heat-processed animal food products such as grilled or broiled meats.
“Mount Sinai researchers showed that consumption of such foods by mice raised the body’s level of AGEs, which, among other effects, suppressed levels of sirtuin, or SIRT1, a key ‘host defense’ shown to protect against Alzheimer’s disease as well as metabolic syndrome, a pre-diabetic state.”
According to the article, the studies suggest that reducing the intake of AGEs could open “new therapeutic avenues” for the treatment of Alzheimer’s dementia, as well as diabetes.
Doctor Helen Vlassara, Professor and Director of the Division of Experimental Diabetes and Aging in the Brookdale Department of Geriatrics at Mount Sinai, was quoted as saying:
“Age-associated dementia or Alzheimer’s disease is currently epidemic in our society and is closely linked to diabetes. Our studies of both animals and human subjects confirm that AGE-rich foods are a lifestyle-driven reality with major health implications. The findings point to an easily achievable goal that could reduce the risk of these conditions through the consumption of non-AGE-rich foods, for example, foods that are cooked or processed under lower heat levels and in the presence of more water – cooking methods employed for centuries.
“While more research needs to be done to discover the exact connection of food AGEs to metabolic and neurological disorders, the new findings again emphasize the importance of not just what we eat, but also how we prepare what we eat. By cutting AGEs, we bolster the body’s own natural defenses against Alzheimer’s disease as well as diabetes.”
Dr. Vlassara’s team also conducted a clinical study of healthy humans over the age of 60, studying them for a nine-month period. According to the article, the study showed that those with high blood levels of AGEs developed cognitive decline, signs of insulin resistance and SIRT1 suppression, while those with low blood AGEs remained healthy.
The Mendota Reporter, a publication covering news in and around Mendota, Illinois, recently interviewed AGE Foundation Advisory Board member Pat Baird about Advanced Glycation End-products.
The article based off that interview, titled “Four numbers you need to know for good health,” stated:
“Advanced Glycation End-products (AGEs) are markers for the aging of our internal organs, tissues and body systems. Research shows that AGEs are linked to nearly every chronic disease we face today, such as obesity, kidney, heart and eye disease, and dementia.”
25 Feb 2014
Our skin can look younger if we avoid certain unhealthy foods, according to a recent Jewish World Review article.
Gretel H. Schueller’s article “Turn back time by avoiding these foods that age your skin” stated that while wrinkles are a natural part of aging, that doesn’t mean we can’t do anything to prevent them.
“While plenty of us spend lots of money on creams and cleansers, the best place to find anti-aging products is in your grocery store or garden. What we eat is just as important–if not more so–as what we slather on our skin.
“Nourishing our skin from the inside out can help beat the clock. And just as some foods can help slow the effect of time, other foods can speed up our skin’s aging process, contributing to wrinkles and sagging.”
The Bermuda Sun recently featured an article about diabetes, and Advanced Glycation End-products were also addressed in the article.
Written by Bermuda Sun columnist Colin Ayliffe, the article is titled “Balancing our blood sugar prevents diabetes onset.”
“Balancing our blood sugar is essential in preventing the onset of Type 2 diabetes, a debilitating condition that is all too prevalent in Bermuda. Diabetes is a serious and sometimes fatal disease. But it can be prevented.
A group of recent Daily Mail articles – written by the co-authors of an anti-sugar book – focused on the negative health effects of sugar, including Advanced Glycation End-products.
Dermatologist Patricia Farris and nutritionist Brooke Alpert first teamed up to write “The Sugar Detox,” a book designed to help people improve their health through a three-day detox plan to get sugar out of one’s system.
A recent Natural Society article titled “8 Foods that Speed Up Ageing While Promoting Sickness” encouraged readers to avoid certain foods should they want to age gracefully and avoid illness.
Author Paul Fassa wrote:
“Eating what’s quick, convenient, and tasty may fit your lifestyle for now, but you may be subjecting yourself to progressively worsening health. If you don’t shift to a healthier diet, someday sooner rather than later you’ll be a young person in an old person’s body, wondering what happened.”
09 Feb 2014
By: Pat Baird, AGE Advisory Board
As a dietitian, I am very conscious of how the foods we eat and the way we prepare them help determine the levels of Advanced Glycation End-products (AGEs) in our bodies. It’s important that everyone learns how to lower their AGE levels through their diet, and my goal is to help others accomplish that.
But AGEs are not solely a result of our diet. They are also a result of our lifestyle.
Inactivity is a key AGE accelerator. Without enough exercise, our AGE levels will climb higher and higher. We use protein and sugar when we exercise for energy and recovery, but when we are inactive, our bodies do not use that protein and sugar for their intended function. Instead, the excess protein and sugar combine to form harmful AGEs inside our bodies.
08 Feb 2014
By: Pat Baird, AGE Advisory Board
Diets and weight loss are always a hot topic, but even more so this time of year as people strive to keep their recent New Year’s resolutions. But reaching and maintaining a healthy weight is always important, as doing so will improve a number of important health markers, including the control of your Advanced Glycation End-product (or AGE) levels.
I can certainly appreciate the need for a healthy diet, as nutrition is at the heart of everything I do. Allow me to make a couple suggestions for you to follow not just for the New Year, but throughout your life.
First, cut down on sugar. Excessive consumption of processed foods leads to an overabundance of sugar in our body, which in turn leads to increased AGE levels. AGEs prematurely age our bodies and diminish our appearance, all while leading to a wide variety of other health concerns.
AGEs have been gaining attention all around the world, and recent AGE Foundation blogs have highlighted AGE articles or studies from England, South Africa, Denmark and Italy. AGE awareness exists Down Under as well, as evidenced by an article that was recently published in Australia.
Author Caitlin Bishop wrote:
“It’s easy to tell when your skin sends out an SOS. Your once clear complexion may have erupted in a seemingly unstoppable outbreak of acne; it may appear red and flushed or dry and cracked. Too long spent in the sun might have fast tracked your path to fine lines and wrinkles, and pigmentation may be starting to rear its head. Here, we get to know some of the most common skin concerns, investigating the causes, symptoms and cures.”
03 Feb 2014
Mail Online, website for British newspaper Daily Mail, recently featured an article about Advanced Glycation End-products and a scanner capable of measuring them. The scanner’s technology was developed by Dr. Andries Smit, a member of the AGE Foundation’s Advisory Board.
Written by Bianca London, the article is titled “Is your roast chicken giving you wrinkles? New scanner reveals damage caused by baking and frying food.”
The AGE Foundation is pleased to announce the addition of Dr. Ovidiu Alin Stirban to the AGE Advisory Board.
Dr. Stirban currently serves as the Director of Endocrinology and Diabetes Complications at the Institute for Metabolic Research in Neuss, Germany and brings a wealth of experience and knowledge to the AGE Advisory Board.
Seen as a leader in the medical research industry, Dr. Stirban’s expertise is centered on Diabetic Neuropathy and in vivo effects of Advanced Glycation End-products.
Articles about how AGEs lead to aging skin just keep pouring in. One of the most recent websites to touch on the issue was South Africa’s Beauty Bulletin, which featured an article titled “Does Sugar Cause Wrinkles?”
Said the article:
“During a process called glycation, sugar attaches to protein fibres in your blood stream forming toxic new compounds called Advanced Glycation End products (or AGEs – how ironic!). As these AGEs build up, they cause inflammation and the protein fibres of collagen and elastin are damaged. Skin starts to lose its elasticity and is no longer firm and supple. It cannot spring back into its original position after a smile or a frown, and wrinkles start to appear.
“Sugar also causes damage to the more stable Collagen II and Collagen III and only the weaker, less resilient, Collagen I, is left. Collagen I is easily damaged, so skin loses its elasticity more quickly this way.”
Written by Amy Lawrenson, the article discussed various health issues associated with excessive sugar consumption, including AGEs.
Lawrenson quoted Simon Capewell, professor of clinical epidemiology at the University of Liverpool, as saying:
“Sugar is the new tobacco. Everywhere, sugary drinks and junk foods are now pressed on unsuspecting parents and children by a cynical industry focused on profit not health.
“The obesity epidemic is generating a huge burden of disease and death.”
27 Jan 2014
Those who follow the AGE Foundation are constantly seeing articles about the role that Advanced Glycation End-products play in aging and damaging our skin, in addition to articles about various other health issues associated with AGEs, such as diabetes. But did you ever consider that AGEs could play a role in hip fractures?
According to the article, which was written by Cole Petrochko, researchers believe that patients with the highest level of serum carboxy-methyl-lysine are at the greatest risk of hip fracture.
Female First, an England-based women’s website that covers entertainment, lifestyle, fashion, beauty and other topics, recently featured an article titled “Healthy diet tips for glowing and youthful skin.”
Written by Taryn Davies, the article features advice from Dr. Stefanie Williams, a dermatologist who wrote the book “Future Proof Your Skin: Slow down your biological clock by changing the way you eat.” For Davies’ article, Williams provided 10 tips on how to maintain healthy skin, and she made it a point to encourage readers to avoid excessive AGEs.
Food Consumer highlighted a recent study that involved the link between diabetes and AGEs. According to the article, “High-heat treated food may boost risk of diabetes mellitus,” the study found that eating foods with high levels of Advanced Glycation End-products may increase the risk of type 2 diabetes mellitus.
“For the study, 74 overweight women who did not have type 2 diabetes mellitus were randomized to follow a diet either high or low in AGEs for four weeks. Fasting insulin concentrations and urinary AGEs were measured before and after intervention.”
Dr. Jaime Uribarri, a member of the AGE Foundation’s Advisory Board, recently collaborated with Dr. Helen Vlassara to write the report “Advanced Glycation End Products (AGE) and Diabetes: Cause, Effect, or Both?”
Referring to Uribarri’s and Vlassara’s study, the Food Consumer article stated:
“A new report suggests that patients with type 2 diabetes mellitus may [be] better off avoiding dietary intake of advanced glycation end products (AGEs), which are found [in] high [amounts] in the blood of type 2 diabetics.”
Everyone would love to look and feel younger, so aging is a very popular topic in the media, and Advanced Glycation End-products are gaining more and more traction in the media as well. One need only look at all the articles and blogs shared on this website to get a sample of how ubiquitous the topics of aging and AGEs are.
Add xStylish.com to the list of sources that have touched on AGEs and their relation to premature aging. The women’s interest website recently featured a blog by Melissa William titled “Eight Causes Of Aging.”
It should come as no surprise to those that follow the AGE Foundation that the very first cause of aging to be listed was the accumulation of AGEs:
“AGE is short for Advanced Glycation End-products, which are harmful compounds that affect nearly every cell and molecule in your body. Glycation refers to the way sugars, or glucose, bind with proteins in a way that stiffens body cells. Glycation makes your body cells less pliable and vulnerable to damage and premature aging.”
07 Jan 2014
“Although the scientific knowledge [about glycation] has been around for decades, it’s become a veritable beauty buzzword these days: anti-glycation diets, anti-glycation skincare,” Telfer wrote.
AGE Foundation Advisory Board member Pat Baird instructed the public on how to keep their AGE levels in check in a recent ExpertBeacon article titled, “Reduce advanced glycation end-products to slow aging and prevent degenerative diseases.”
A registered dietitian, Baird emphasized the importance of being mindful of our AGE levels. She wrote:
“When it comes to our overall health, we often think about our cholesterol, blood pressure and body mass index (BMI). However, there’s a fourth medical marker that’s just as important but rarely discussed—Advanced Glycation End-products (AGEs). At high levels, AGEs are harmful compounds when proteins combine with excess sugar. AGEs can also [be] consumed through the food we eat.
“Over time, AGEs can reach high levels in our body and cause damage that accelerates the aging process from the inside out and impacting nearly every age-related health concern we discuss today. And as more studies are released surrounding AGEs, the more we learn about the role they play in the rise of diabetes, osteoporosis, heart disease, Alzheimer’s and more.”
03 Jan 2014
The Huffington Post recently cautioned the public about AGEs and other consequences that certain diets have on our skin.
In an article titled “The 3 Worst Food Mistakes You Can Make For Your Skin,” Rebecca Adams – Associate Editor for HuffPost Style – wrote:
“In 2008 alone, Americans spent $35 billion on cosmetics and skincare. But are all these dollars wasted when we follow a diet that causes acne, premature aging and other skin conditions? It sure seems so.”
02 Jan 2014
A recent Flixya blog titled “Will how you will Prepare Food Increase Your Possibility of Diabetes?” warned of the risks that come with caramelizing food via broiling, grilling or searing under high temperatures. It stated:
“In the course of the browning action in cooking, water is removed in the form of steam and the product’s sugars will be degraded. The end products are AGEs, which happen to be a sugar molecule that bonds with a protein molecule without the reaction restricted by an enzyme. This process produces a non-functioning glycated protein structure, also called AGEs.”
As a recent The Daily Meal article stated, it’s no secret that fast food is typically high in calories, saturated and trans fats, sugar, and sodium. Likewise, it’s no secret that excessive consumption of fast food can lead to obesity, heart disease, type 2 diabetes, and stroke.
But as noted in that particular article, titled “The Side Effects of Fast Food That No One Talks About,” there are additional risks that come with an unhealthy diet, including increased AGE levels.
AGEs are a global issue, not just an American issue. Thankfully other nations are also recognizing the problems that AGEs cause in our lives, and one such example of that recognition is an article on AGEs that was just published on the Italian website for Marie Claire. The article also cites the AGE Foundation and quotes AGE Advisory board member Michelle Davenport.
If you’re not brushed up on your Italian, worry not; an English version of the article can be read here thanks to Google Translate. While the translation isn’t perfect, it nevertheless helps convey the article’s message.
The AGE Foundation’s own Pat Baird just made a television appearance on Fox 9 Morning News in Minnesota, educating viewers on the subject of “prescriptive eating.” Naturally, one of the health issues that she discussed was AGEs.
A member of the AGE Advisory board in addition to a media spokesperson and award-winning author, Baird is a registered dietitian. On her television segment, she discussed what types of natural foods address certain health needs.
The Diet Detective – with some help from a nutrition expert – is on the case when it comes to AGEs and is laying down the law regarding excessive sugar consumption.
One of the nation’s leading nutrition and public health advocates, Charles Platkin has made a name for himself with his column, the Diet Detective, which appears in more than 100 daily newspapers nationally.
In a recent column, Platkin interviewed nutrition guru Brooke Alpert about the negative effects of sugar, and she echoed what many other experts have been saying lately about sugar, AGEs and premature aging. Alpert is a registered dietitian and nutritionist, as well as founder of B nutritious and co-author of the book “The Sugar Detox.”
According to a Science Codex article titled “Potential biological factor contributing to racial disparities in prostate cancer,” researchers with the American Association for Cancer Research (AACR) have found that AGEs may play a role in prostate cancer rates, specifically higher rates among African-Americans.
The link between excessive sugar consumption, AGEs and skin damage continues to be highlighted by a variety of sources, with the latest being Rodale News.
In a recent article titled “11 Weird Things Sugar’s Doing to Your Body,” author Leah Zerbe explored some of the negative effects of sugar as outlined in the upcoming book Sugar Smart Diet by Anne Alexander and Julia VanTine, due for release December 24.
As previously featured on this site, Cosmopolitan recently published a blog post about women’s skin care that addressed the need to avoid excess sugar because of the harmful effects of AGEs. Of course, AGEs do not discriminate against gender; men have a need to be aware of AGEs and the need for a healthy diet as well.
That was evidenced in November when the website for “Details” – a monthly men’s magazine dedicated to fashion and lifestyle – published a blog titled “4 Surprising Ways You May Be Aging Your Skin.”
“You already know that if you eat, sleep, and exercise like crap, you’re probably going to look and feel like it, too,” the article states. “But how you treat your body today can affect more than just the way you look right now; it can also impact how you’ll look in, say, 10 years.”
The November issue of Skin Inc. magazine addressed the effects of AGEs with an article titled “Glycation and the Skin.” Skin Inc. claims to be the leading industry publication for day spa, medical spa and wellness professionals, providing information about skin science, spa treatment trends, and more.